internal reflection fluorescence tirf microscopy (Nikon)
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Internal Reflection Fluorescence Tirf Microscopy, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluorescence+microscopy+system/N-STORM/pmc13673699-59-1-9
Average 99 stars, based on 1 article reviews
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1) Product Images from "Simultaneous activation and release of a microtubule inhibitor from amphiphilic polymeric nanoparticles"
Article Title: Simultaneous activation and release of a microtubule inhibitor from amphiphilic polymeric nanoparticles
Journal: Nanoscale Advances
doi: 10.1039/d6na00763e
Figure Legend Snippet: (a) Schematic representation of light-controlled inhibition of microtubule polymerisation by proPST-1-loaded polymer nanoparticles (proPST-1@PN). Under dark conditions, the encapsulated photocaged prodrug remains inactive, allowing normal microtubule formation. Upon 365 nm irradiation, photolytic uncaging and release of active cis -PST-1 suppress microtubule assembly. Created in BioRender. Singh, H. (2026) https://BioRender.com/fac5r0eT . (b) Tubulin polymerisation kinetics monitored by absorbance at 340 nm for control samples, empty polymer nanoparticles (PN control), and proPST-1@PN under dark and irradiated conditions. Irradiation of proPST-1@PN results in pronounced inhibition of tubulin polymerisation, whereas no inhibition is observed in the dark. (c) Fluorescence microscopy images of microtubule structures formed in the presence of control samples, proPST-1@PN under dark conditions, and irradiated proPST-1@PN. Normal microtubule growth and network formation are observed in control and dark conditions, while irradiation results in substantial disruption of microtubule assembly. Scale bars: 10 µm.
Techniques Used: Inhibition, Polymer, Irradiation, Control, Fluorescence, Microscopy, Disruption
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